{"id":691,"date":"2026-06-16T10:53:03","date_gmt":"2026-06-16T02:53:03","guid":{"rendered":"https:\/\/www.kz-hub.tech\/?p=691"},"modified":"2026-06-16T10:53:03","modified_gmt":"2026-06-16T02:53:03","slug":"%e4%bd%bf%e7%94%a8telomerehunter2%e8%ae%a1%e7%ae%97%e7%ab%af%e7%b2%92%e9%95%bf%e5%ba%a6","status":"publish","type":"post","link":"https:\/\/www.kz-hub.tech\/index.php\/2026\/06\/16\/%e4%bd%bf%e7%94%a8telomerehunter2%e8%ae%a1%e7%ae%97%e7%ab%af%e7%b2%92%e9%95%bf%e5%ba%a6\/","title":{"rendered":"\u4f7f\u7528telomerehunter2\u8ba1\u7b97\u7aef\u7c92\u957f\u5ea6"},"content":{"rendered":"<p>\u5b98\u65b9github\u94fe\u63a5\uff1a<a href=\"https:\/\/github.com\/ferdinand-popp\/telomerehunter2\">https:\/\/github.com\/ferdinand-popp\/telomerehunter2<\/a><\/p>\n<p>\u53c2\u8003\u4ee3\u7801\uff1a<\/p>\n<pre><code class=\"language-bash\">telomerehunter2 -ibt TUMOR_FILE -ibc CONTROL_FILE -o OUTPUT_DIRECTORY -p ID_OF_SAMPLE -b BANDING_FILE [options]<\/code><\/pre>\n<p>\u6279\u91cf\u8fd0\u884c\u811a\u672c\uff1a<\/p>\n<pre><code>perl -ne &#039;chomp; next if \/^$\/; @a = split \/\\t\/; print &quot;telomerehunter2 -p $a[0] -ibc ..\/align\/$a[1]_bqsr.bam -ibt ..\/align\/$a[0]_bqsr.bam -o \/group_homes\/prolinying\/home\/share\/Phyllodes\/LCM-WGS\/telomerehunter2 -b \/home\/zhoukaiwen\/database\/telomerehunter2\/hg38_cytoBand.txt &gt; log\/$a[0].log 2&gt;&amp;1 &amp;&amp; echo $a[0] telomerehunter2 ok\\n&quot;;&#039; ..\/mutect2\/sample_pair.txt &gt; RunTelomereHunter.sh\n\nnohup bash -c &quot;cat RunTelomereHunter.sh | parallel -j 4&quot; &gt; log\/telomerehunter.log 2&gt;&amp;1 &amp;<\/code><\/pre>\n<p>\u7ed3\u679c\u6587\u4ef6\u89e3\u8bfb\uff1a<br \/>\n\u8f93\u51fa\u6587\u4ef6\u4e3a\u201cTumor_summary.tsv\u201d\u7684\u5373\u4e3a\u7ed3\u679c\uff0c\u5176\u4e2dtel_content\u4e3a\u7aef\u7c92\u957f\u5ea6<\/p>\n<pre><code>PID     sample  tel_content     total_reads     read_lengths    repeat_threshold_set    repeat_threshold_used   intratelomeric_reads    junctionspanning_reads  subtelomeric_reads      intrachromosomal_reads  tel_read_countgc_bins_for_correction  total_reads_with_tel_gc TCAGGG_arbitrary_context_norm_by_intratel_reads TGAGGG_arbitrary_context_norm_by_intratel_reads TTGGGG_arbitrary_context_norm_by_intratel_reads TTCGGG_arbitrary_context_norm_by_intratel_reads       TTTGGG_arbitrary_context_norm_by_intratel_reads ATAGGG_arbitrary_context_norm_by_intratel_reads CATGGG_arbitrary_context_norm_by_intratel_reads CTAGGG_arbitrary_context_norm_by_intratel_reads GTAGGG_arbitrary_context_norm_by_intratel_reads       TAAGGG_arbitrary_context_norm_by_intratel_reads TCAGGG_singletons_norm_by_all_reads     TGAGGG_singletons_norm_by_all_reads     TTGGGG_singletons_norm_by_all_reads     TTCGGG_singletons_norm_by_all_reads   TTTGGG_singletons_norm_by_all_reads     ATAGGG_singletons_norm_by_all_reads     CATGGG_singletons_norm_by_all_reads     CTAGGG_singletons_norm_by_all_reads     GTAGGG_singletons_norm_by_all_reads   TAAGGG_singletons_norm_by_all_reads\nFETB06-BLPT-M   tumor   2704.045416     2376228562      90      6 per 100 bp    5       1116591 13770   144649  53817   1328827 48-52   412933523       0.0943326607504448      0.1466427725102566      0.083708358745503    0.0422858504143415       0.0132438824959183      0.0180191314456233      0.0006931812991507      0.0899380346071211      0.0407203712012724      0.0246464461920255      4.965852270569585e-07   7.01111007014316e-07    4.717559657041106e-07 2.2725086661928608e-08  7.221527539235092e-07   3.577096974562837e-07   0       5.260436727298289e-07   1.658089656444421e-07   1.392963645388587e-07\nFETB06-BLPT-M   control 1775.935218     2160559050      90      6 per 100 bp    5       491170  6264    47324   23042   567800  48-52   276569773       0.0725003562921188      0.1134841297310503      0.0863672455565282   0.0403058004356943       0.0168577071075187      0.0165054868986298      0.0011767819695828      0.0497526314717918      0.0713927967913349      0.0369810859783781      3.3833835738023454e-07  2.615063911352018e-07   3.813827722042589e-07 3.7027453612063976e-08  4.670087586821568e-07   8.192324111669153e-08   0       5.688342561153328e-07   1.383901078750891e-07   2.2077619216193147e-07\nFETB06-BLPT-M   log2(tumor\/control)     0.6065404262406129                                                                                              0.37976927592854426     0.3698154107408493      -0.0451125885059767140.06918752014628017      -0.34808220635008424    0.12658377480988212     -0.7635424085069049     0.8541585240923169      -0.8100278073435476     -0.5854079539855125     0.5535745987608439      1.422796678527075       0.306801086086286     -0.7043095422598166     0.6288544288572661      2.126444531406144               -0.11282577035913463    0.2607811957223489      -0.6644269987342165<\/code><\/pre>\n","protected":false},"excerpt":{"rendered":"<p>\u5b98\u65b9github\u94fe\u63a5\uff1ahttps:\/\/github.com\/ferdinand-popp\/telomerehu&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-691","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/www.kz-hub.tech\/index.php\/wp-json\/wp\/v2\/posts\/691","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.kz-hub.tech\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.kz-hub.tech\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.kz-hub.tech\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.kz-hub.tech\/index.php\/wp-json\/wp\/v2\/comments?post=691"}],"version-history":[{"count":1,"href":"https:\/\/www.kz-hub.tech\/index.php\/wp-json\/wp\/v2\/posts\/691\/revisions"}],"predecessor-version":[{"id":692,"href":"https:\/\/www.kz-hub.tech\/index.php\/wp-json\/wp\/v2\/posts\/691\/revisions\/692"}],"wp:attachment":[{"href":"https:\/\/www.kz-hub.tech\/index.php\/wp-json\/wp\/v2\/media?parent=691"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.kz-hub.tech\/index.php\/wp-json\/wp\/v2\/categories?post=691"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.kz-hub.tech\/index.php\/wp-json\/wp\/v2\/tags?post=691"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}